Peripheral neuropathy often presents as burning, tingling, stabbing, or a “pins and needles” sensation in the hands or feet. Typically, this sensation will begin in the fingers or toes, but it may spread to affect the hands, wrists, arms, feet, ankles and even lower parts of the legs. The pain usually presents in a symmetrical pattern, meaning both hands or both feet are affected equally. Use of the hands for activities such as gripping or lifting objects may worsen the pain. Standing or walking may worsen the pain in the lower limbs. As the condition progresses, loss of touch, pain, and temperature sensations may occur.